Reaction: SLC9B1/C2 exchange Na+ for H+
- in pathway: Stimuli-sensing channels
The sodium/hydrogen exchanger 9B1 (SLC9B1 aka Na+/H+ exchanger like domain containing 1, NHEDC1) is specifically expressed on the plasma membrane of the testis and may be implicated in infertility (Ye et al. 2006). Sodium/hydrogen exchanger 9C2 (SLC9C2), also localized to the plasma membrane, may be involved in pH regulation although this protein has not been fully characterized.
Reaction - small molecule participants:
H+ [extracellular region]
Na+ [cytosol]
H+ [cytosol]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-2872444
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Reaction input - small molecules:
hydron
sodium(1+)
Reaction output - small molecules:
hydron
sodium(1+)
Reactome.org link: R-HSA-2872444