Reaction: SLC9C1 exchanges Na+ for H+
- in pathway: Stimuli-sensing channels
The sperm-specific Na+/H+ exchanger SLC9C1 (aka sodium/hydrogen exchanger 10, NHE10) is localized to the flagellar membrane and is involved in pH regulation of spermatozoa required for sperm motility and fertility. The activity of human SLC9C1 is inferred from experiments using mouse Slc9c1 (Wang et al. 2003).
Reaction - small molecule participants:
H+ [extracellular region]
Na+ [sperm flagellum]
H+ [sperm flagellum]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-2872463
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Reaction input - small molecules:
hydron
sodium(1+)
Reaction output - small molecules:
hydron
sodium(1+)
Reactome.org link: R-HSA-2872463