Reaction: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol
- in pathway: Stimuli-sensing channels
The microsomal Na+/(PO4)3- transporter isoform 1 (SLC17A3, NPT4 isoform 1) is a member of the anion-cation symporter family. It is expressed in liver, kidney and intestine and may function as a cotransporter of sodium (Na+) and phosphate ((PO4)3- or Pi) across the ER membrane (Melis et al. 2004).
Reaction - small molecule participants:
Pi [endoplasmic reticulum lumen]
Na+ [endoplasmic reticulum lumen]
Pi [cytosol]
Na+ [cytosol]
Reactome.org reaction link: R-HSA-2872498
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Reaction input - small molecules:
hydrogenphosphate
sodium(1+)
Reaction output - small molecules:
hydrogenphosphate
sodium(1+)
Reactome.org link: R-HSA-2872498