Reaction: PP2A dephosphorylates BANF1
- in pathway: Initiation of Nuclear Envelope (NE) Reformation
The PP2A complex that contains the regulatory subunit PPP2R2A (B55-alpha) is the only phosphatase essential for mitotic exit (Schmitz et al. 2010). It is also necessary for BANF1 (BAF) dephosphorylation in anaphase/telophase. ANKLE2 binds the PP2A complex that contains the B55-alpha regulatory subunit and facilitates BANF1 dephosphorylation (Asencio et al. 2012).
Reaction - small molecule participants:
Pi [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-2995388
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Reaction input - small molecules:
water
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-2995388