Reaction: TCN2:RCbl is degraded to release RCbl
- in pathway: Transport of RCbl within the body
A lysosomal protease that is sensitive to treatment with chloroquine but otherwise uncharacterized hydrolyzes transcobalamin 2 (TCN2) bound to cobalamins (RCbl), releasing the latter (Youngdahl Turner et al. 1979).
Reaction - small molecule participants:
RCbl [lysosomal lumen]
Reactome.org reaction link: R-HSA-3000263
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Reaction input - small molecules:
Reaction output - small molecules:
R-cob(III)alamin
Reactome.org link: R-HSA-3000263