Reaction: ABCC1 transports cytosolic RCbl to extracellular region
- in pathway: Transport of RCbl within the body
Multidrug resistance associated protein 1 (ABCC1, MRP1) mediates the ATP dependent export of free cobalamins (RCbl) from small intestine cells to the portal vein (Shah et al. 2011, Nielsen et al. 2012).
Reaction - small molecule participants:
Pi [cytosol]
ADP [cytosol]
RCbl [extracellular region]
H2O [cytosol]
ATP [cytosol]
RCbl [cytosol]
Reactome.org reaction link: R-HSA-3095901
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Reaction input - small molecules:
water
ATP(4-)
R-cob(III)alamin
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
R-cob(III)alamin
Reactome.org link: R-HSA-3095901