Reaction: p-MAPKAPK3 phosphorylates BMI1
- in pathway: Oxidative Stress Induced Senescence
In response to stress-activated p38 signaling, MAPKAPK3 phosphorylates BMI1, leading to the dissociation of the PRC1.4 complex from chromatin and transcription of p14-ARF (Voncken et al. 2005).
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-3229102
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-3229102