Reaction: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane
- in pathway: Gluconeogenesis
The SLC37A1 and SLC37A2 transport proteins mediate the exchange of G6P (glucose-6-phosphate) and Pi (orthophosphate) across lipid bilayer membranes in vitro, and both proteins are located in the endoplasmic reticulum membrane. Their physiological function, however, is unknown (Pan et al. 2011; Chou et al. 2013).
Reaction - small molecule participants:
Pi [cytosol]
G6P [endoplasmic reticulum lumen]
Pi [endoplasmic reticulum lumen]
G6P [cytosol]
Reactome.org reaction link: R-HSA-3257122
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Reaction input - small molecules:
hydrogenphosphate
alpha-D-glucose 6-phosphate(2-)
Reaction output - small molecules:
hydrogenphosphate
alpha-D-glucose 6-phosphate(2-)
Reactome.org link: R-HSA-3257122