Reaction: SUCNR1 binds SUCCA
- in pathway: Class A/1 (Rhodopsin-like receptors)
SUCNR1 (GPR91) is activated by the citric acid cycle intermediate succinate (SUCCA) (He et al. 2004), signalling via Gi to have a role in the stimulation of hematopoietic progenitor cell (HPC) growth (Hakak et al. 2009).
Reaction - small molecule participants:
SUCCA [extracellular region]
Reactome.org reaction link: R-HSA-3296244
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Reaction input - small molecules:
succinate(2-)
Reaction output - small molecules:
Reactome.org link: R-HSA-3296244