Reaction: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1
- in pathway: Glycogen synthesis
Phosphorylated glycogen synthase 1 (GYS1-b) complexed with oligo-D-glucose-GYG1 catalyzes the polyglucosylation of the latter. (Here the addition of four glucose residues is annotated.) This reaction is allosterically activated by glucose-6-phosphate (G6P) (Cameron et al. 2009; Roach et al. 2012). Glucose-6-phosphate (G6P) activates the phosphorylated ("b") form of GYS1 ("muscle") glycogen synthase (Roach et al. 2012).
Reaction - small molecule participants:
UDP [cytosol]
UDP-D-glucose(2-) [cytosol]
Reactome.org reaction link: R-HSA-3322041
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Reaction input - small molecules:
UDP-D-glucose(2-)
Reaction output - small molecules:
UDP(3-)
Reactome.org link: R-HSA-3322041