Reaction: TXNRD2 catalyzes the reduction of TXN2 by NADPH
- in pathway: Detoxification of Reactive Oxygen Species
Thioredoxin reductase 2 (TXNRD2) in the mitochondrial matrix regenerates reduced thioredoxin (TXN) by reacting oxidized thioredoxin with NADPH (Gasdaska et al. 1999, Cao et al. 2007).
Reaction - small molecule participants:
NADP+ [mitochondrial matrix]
H+ [mitochondrial matrix]
NADPH [mitochondrial matrix]
Reactome.org reaction link: R-HSA-3323050
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Reaction input - small molecules:
hydron
NADPH
Reaction output - small molecules:
NADP(+)
Reactome.org link: R-HSA-3323050