Reaction: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
- in pathway: TP53 Regulates Metabolic Genes
Peroxiredoxin 1 (PRDX1), PRDX2, and PRDX5 in the cytosol reduce hydrogen peroxide (H2O2) with thioredoxin yielding oxidized thioredoxin and water (Yamashita et al. 1999, Lee et al. 2007, Nagy et al. 2011).
Reaction - small molecule participants:
H2O [cytosol]
H2O2 [cytosol]
H2O [cytosol]
H2O2 [cytosol]
Reactome.org reaction link: R-HSA-3341343
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Reaction input - small molecules:
hydrogen peroxide
hydrogen peroxide
Reaction output - small molecules:
water
water
Reactome.org link: R-HSA-3341343