Reaction: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle
- in pathway: HDL assembly
Pre-beta HDL (lipid-poor apoA-I) interacts with phospholipid- and cholesterol-rich membrane patches formed through the action of ABCA1, binding these two lipids to form a discoidal (small nascent) HDL particle (HDL 3c - Kontush and Chapman 2006).
Reaction - small molecule participants:
CHOL [plasma membrane]
PL [plasma membrane]
Reactome.org reaction link: R-HSA-349657
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Reaction input - small molecules:
cholesterol
phospholipid
Reaction output - small molecules:
Reactome.org link: R-HSA-349657