Reaction: Arginine<=>Agmatine+CO2
- in pathway: Agmatine biosynthesis
Agmatine is polyamine formed by decarboxylation of L-arginine by arginine decarboxylase (ADC). Human ADC is a 460-amino acid protein that shows about 48% identity to mammalian ornithine decarboxylase (ODC) but has no ODC activity.
Reaction - small molecule participants:
CO2 [cytosol]
AGM [cytosol]
L-Arg [cytosol]
Reactome.org reaction link: R-HSA-350598
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Reaction input - small molecules:
L-argininium(1+)
Reaction output - small molecules:
carbon dioxide
agmatinium(2+)
Reactome.org link: R-HSA-350598