Reaction: Agmatine + H2O <=> putrescine + urea
- in pathway: Agmatine biosynthesis
As it hydrolyzes a guanidino group within agmatine and also contains signature amino acid residues that act as ligand binding sites for the potential Mn(++) cofactor, agmatinase is classified as a member of the arginase superfamily (Morris, 2003).
Reaction - small molecule participants:
Urea [cytosol]
Putrescine [cytosol]
H2O [cytosol]
AGM [cytosol]
Reactome.org reaction link: R-HSA-350604
======
Reaction input - small molecules:
water
agmatinium(2+)
Reaction output - small molecules:
urea
1,4-butanediammonium
Reactome.org link: R-HSA-350604