Reaction: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine
- in pathway: Amino acid transport across the plasma membrane
SLC1A4, associated with the plasma membrane, mediates the exchange of serine and an extracellular sodium ion for a cytosolic sodium ion and any one of the four amino acids alanine, serine, threonine, or cysteine (Zerangue and Kavanaugh 1996).
Reaction - small molecule participants:
Na+ [cytosol]
L-Ser [cytosol]
Na+ [extracellular region]
L-Ser [extracellular region]
Na+ [cytosol]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-352347
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Reaction input - small molecules:
L-serine zwitterion
sodium(1+)
sodium(1+)
Reaction output - small molecules:
sodium(1+)
L-serine zwitterion
sodium(1+)
Reactome.org link: R-HSA-352347