Reaction: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine
- in pathway: Amino acid transport across the plasma membrane
SLC1A4, associated with the plasma membrane, mediates the exchange of alanine and an extracellular sodium ion for a cytosolic sodium ion and any one of the four amino acids alanine, serine, threonine, or cysteine (Zerangue and Kavanaugh 1996).
Reaction - small molecule participants:
L-Ala [cytosol]
Na+ [cytosol]
Na+ [extracellular region]
Na+ [cytosol]
L-Ala [extracellular region]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-352364
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Reaction input - small molecules:
sodium(1+)
L-alanine zwitterion
sodium(1+)
Reaction output - small molecules:
L-alanine zwitterion
sodium(1+)
sodium(1+)
Reactome.org link: R-HSA-352364