Reaction: HDAC10 deacetylates histone
- in pathway: HDACs deacetylate histones
HDAC10 is a class IIb HDAC subfamily member with greatest sequence similarity to HDAC6. Unlike HDAC6, HDAC10 is found in the nucleus. It is able to deacetylate acetylated histone H4 N-terminal peptides (Fischer et al. 2002, Guardiola & Yao 2002, Kao et al. 2002, Tong et al. 2002).
Reaction - small molecule participants:
acetate [nucleoplasm]
H2O [nucleoplasm]
Reactome.org reaction link: R-HSA-3782655
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Reaction input - small molecules:
water
Reaction output - small molecules:
acetate
Reactome.org link: R-HSA-3782655