Reaction: MAOA:FAD deaminates DA to DOPAC
- in pathway: Enzymatic degradation of Dopamine by monoamine oxidase
Dopamine (DA) is oxidatively deaminated to 3,4-dihydroxyphenylacetic acid (DOPAC) by monoamine oxidase A (MAOA), bound to its cofactor FAD (O'Caroll et al.1983).
Reaction - small molecule participants:
DOPAC [cytosol]
NH3 [cytosol]
H2O2 [cytosol]
H2O [cytosol]
O2 [cytosol]
DA [cytosol]
Reactome.org reaction link: R-HSA-379382
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Reaction input - small molecules:
water
dioxygen
dopaminium(1+)
Reaction output - small molecules:
(3,4-dihydroxyphenyl)acetate
ammonia
hydrogen peroxide
Reactome.org link: R-HSA-379382