Reaction: serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate
- in pathway: Cytosolic tRNA aminoacylation
SARS (cytosolic seryl tRNA synthetase) catalyzes the reaction of serine, tRNA(Ser), and ATP to form Ser-tRNA(Ser), AMP, and pyrophosphate. The enzyme, a class II tRNA synthetase, is a homodimer (Hartlein and Cusack 1995; Vincent et al. 1997).
Reaction - small molecule participants:
PPi [cytosol]
AMP [cytosol]
ATP [cytosol]
L-Ser [cytosol]
Reactome.org reaction link: R-HSA-379992
======
Reaction input - small molecules:
ATP(4-)
L-serine zwitterion
Reaction output - small molecules:
diphosphate(3-)
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-379992