Reaction: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
- in pathway: Cytosolic tRNA aminoacylation
RARS (cytosolic arginyl tRNA synthetase) catalyzes the reaction of arginine, tRNA(Arg), and ATP to form Arg-tRNA(Arg), AMP, and pyrophosphate. The enzyme, a class I tRNA synthetase, is a monomer found in the cell as a component of the mutienzyme aminoacyl-tRNA synthetase complex (Ling et al. 2005).
Reaction - small molecule participants:
PPi [cytosol]
AMP [cytosol]
L-Arg [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-379993
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Reaction input - small molecules:
L-argininium(1+)
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-379993