Reaction: asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate
- in pathway: Cytosolic tRNA aminoacylation
NARS (cytosolic asparaginyl tRNA synthetase) catalyzes the reaction of asparagine, tRNA(Asn), and ATP to form Asn-tRNA(Asn), AMP, and pyrophosphate. The enzyme is a class I tRNA synthetase (Beaulande et al. 1998).
Reaction - small molecule participants:
PPi [cytosol]
AMP [cytosol]
L-Asn [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-379996
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Reaction input - small molecules:
L-asparagine zwitterion
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-379996