Reaction: serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate
- in pathway: Mitochondrial tRNA aminoacylation
SARS2 (mitochondrial seryl tRNA synthetase) catalyzes the reaction of serine, mitochondrial tRNA(Ser), and ATP to form Ser-tRNA(Ser), AMP, and pyrophosphate. SARS2 is a class II tRNA synthetase inferred from the biochemical properties of its bovine homologue to function as a dimer (Yokogawa et al. 2000).
Reaction - small molecule participants:
AMP [mitochondrial matrix]
PPi [mitochondrial matrix]
ATP [mitochondrial matrix]
L-Ser [mitochondrial matrix]
Reactome.org reaction link: R-HSA-380239
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Reaction input - small molecules:
ATP(4-)
L-serine zwitterion
Reaction output - small molecules:
adenosine 5'-monophosphate(2-)
diphosphate(3-)
Reactome.org link: R-HSA-380239