Reaction: phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate
- in pathway: Alpha-oxidation of phytanate
VLCS (very long chain acyl-CoA synthetase), associated with the inner surface of the peroxisomal membrane, cayalyzes the reaction of phytanate, CoA-SH, and ATP to form phytanoyl-CoA, AMP, and pyrophosphate (Steinberg et al. 1999).
Reaction - small molecule participants:
PPi [peroxisomal matrix]
Phytanoyl-CoA [peroxisomal matrix]
AMP [peroxisomal matrix]
Phytanate [peroxisomal matrix]
CoA-SH [peroxisomal matrix]
ATP [peroxisomal matrix]
Reactome.org reaction link: R-HSA-389622
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Reaction input - small molecules:
phytanic acid
coenzyme A(4-)
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
phytanoyl-CoA
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-389622