Reaction: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA
- in pathway: Beta-oxidation of very long chain fatty acids
Peroxisomal ACAA1 catalyzes the reaction of 3-ketohexacosanoyl-CoA and CoASH to form tetracosanoyl-CoA + acetyl-CoA (Bout et al. 1991).
Reaction - small molecule participants:
Ac-CoA [peroxisomal matrix]
tetracosanoyl-CoA [peroxisomal matrix]
CoA-SH [peroxisomal matrix]
3-ketohexacosanoyl-CoA [peroxisomal matrix]
Reactome.org reaction link: R-HSA-390250
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Reaction input - small molecules:
coenzyme A(4-)
3-oxohexacosanoyl-CoA(4-)
Reaction output - small molecules:
acetyl-CoA(4-)
tetracosanoyl-CoA(4-)
Reactome.org link: R-HSA-390250