Reaction: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate
- in pathway: Plasmalogen biosynthesis
Peroxisomal alkylglycerone phosphate synthase (AGPS) catalyzes the reaction of 1-palmitoylglycerone phosphate and hexadecanol to form O-hexadecylglycerone phosphate and palmitate. The active form of the enzyme is post-translationally cleaved to remove its 58 aminoterminal residues, has a molecule of FAD as a cofactor, and occurs in the peroxisome as a complex with glyceronephosphate O-acyltransferase (GNPAT) (Biermann et al. 1999; Bierman and van den Bosch 1999; de Vet et al. 2000).
Reaction - small molecule participants:
GO3P [peroxisomal matrix]
PALM [peroxisomal matrix]
HXOL [peroxisomal matrix]
1-Palmitoyl dihydroxyacetone phosphate [peroxisomal matrix]
Reactome.org reaction link: R-HSA-390427
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Reaction input - small molecules:
hexadecan-1-ol
1-palmitoylglycerone 3-phosphate(2-)
Reaction output - small molecules:
1-alkylglycerone 3-phosphate(2-)
hexadecanoic acid
Reactome.org link: R-HSA-390427