Reaction: ATP Hydrolysis By Myosin
- in pathway: Striated Muscle Contraction
The cleft closes like a clam shell around the ATP molecule, triggering a large shape change that causes the myosin head to release actin and be displaced along the actin filament by a distance of about 5 nm. Hydrolysis of ATP occurs, but the ADP remains tightly bound to the protein.
Reaction - small molecule participants:
Pi [cytosol]
Reactome.org reaction link: R-HSA-390593
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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-390593