Reaction: Myosin Binds ATP
- in pathway: Striated Muscle Contraction
A molecule of ATP binds to the large cleft on the side of the myosin head farthest from the actin filament and immediately causes a slight change in the conformation of the domains that make up the actin-binding site. This reduces the affinity of the myosin head for actin and allows it to move along the filament.
Reaction - small molecule participants:
ATP [cytosol]
Reactome.org reaction link: R-HSA-390598
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
Reactome.org link: R-HSA-390598