Reaction: DRD1,5 bind DA
- in pathway: Dopamine receptors
Dopamine receptors 1 (Dearry A et al, 1990) and 5 (Sunahara RK et al, 1991) are members of the D1-like dopamine receptor family. Once activated, they couple to the G protein alpha-s subtype which can activate adenylate cyclase. This increases the intracellular concentration of cAMP, which, in neurons, is typically excitatory.
Reaction - small molecule participants:
DA [extracellular region]
Reactome.org reaction link: R-HSA-390835
======
Reaction input - small molecules:
dopaminium(1+)
Reaction output - small molecules:
Reactome.org link: R-HSA-390835