Reaction: 5-HT2 receptor can bind serotonin
- in pathway: Serotonin receptors
The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. There are three subtypes; 2A (Stam NJ et al, 1992), 2B (Kursar JD et al, 1994; Schmuck K et al, 1994) and 2C (Stam NJ et al, 1994). The actions of these receptors are mediated by coupling with the G protein alpha-q/11 subtype which activates phospholipase C, increasing cellular levels of inositol trisphosphate (IP3) and diacylglycerol (DAG) (Lucaites VL et al, 1996).
Reaction - small molecule participants:
5HT [extracellular region]
Reactome.org reaction link: R-HSA-390930
======
Reaction input - small molecules:
serotonin(1+)
Reaction output - small molecules:
Reactome.org link: R-HSA-390930