Reaction: DP1 receptor can bind PGD2
- in pathway: Prostanoid ligand receptors
DP1 is a G-protein-coupled receptor encoded by the PTGDR gene (Boie Y et al, 1995). Its activity is mainly mediated by the G protein alpha s subunit that stimulates adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+ (Seiler S et al, 1990).
Reaction - small molecule participants:
PGD2 [extracellular region]
Reactome.org reaction link: R-HSA-391935
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Reaction input - small molecules:
prostaglandin D2
Reaction output - small molecules:
Reactome.org link: R-HSA-391935