Reaction: Acetylcholine binds Muscarinic Acetylcholine Receptor M3
- in pathway: Acetylcholine regulates insulin secretion
Intrapancreatic parasympathetic (vagal) nerve endings release acetylcholine during preabsorptive and absorptive phases of feeding. The acetylcholine binds Muscarinic Acetylcholine Receptor M3 on pancreatic islet beta cells (inferred from experiments with knockout mice).
Reaction - small molecule participants:
AcCho [extracellular region]
Reactome.org reaction link: R-HSA-400012
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Reaction input - small molecules:
acetylcholine
Reaction output - small molecules:
Reactome.org link: R-HSA-400012