Reaction: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites
- in pathway: Trafficking of GluR2-containing AMPA receptors
GluR2 containing AMPA receptors are trafficked to the plasmamembrane by the activation of Ca activated PKC that binds PICK.The PICK interaction delivers GluR2 containing AMPA receptors to the Plasmamembrane. This reaction is a part of constitutive recycling of AMPA receptor that delivers the AMPA receptors from the endosome to the plasmamembrane and back to endosome from the plasmamembrane.
Reaction - small molecule participants:
Pi [cytosol]
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-416639
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
Reactome.org link: R-HSA-416639