Reaction: P2Y10 receptor can bind to LPA
- in pathway: P2Y receptors
The P2Y10 receptor is expressed during myeloid differentiation of HL60 cells (Adrian K et al, 2000) and is the first dual lysophospholipid receptor, able to bind both sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) (Murakami M et al, 2008). The effects of this receptor are mediated by coupling with the G protein alpha q/11 subunit.
Reaction - small molecule participants:
LPA [extracellular region]
Reactome.org reaction link: R-HSA-417842
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Reaction input - small molecules:
1-octadec-9-enoylglycero-3-phosphate
Reaction output - small molecules:
Reactome.org link: R-HSA-417842