Reaction: Activation of Protein Kinase C novel isoforms
- in pathway: Effects of PIP2 hydrolysis
Activation of the novel Protein Kinase C (nPKC) isoforms (delta, epsilon, eta and theta) requires binding to the membrane lipid diacylglycerol (DAG). nPKC activation is sensitive to DAG concentration.
Reaction - small molecule participants:
DAG [plasma membrane]
Reactome.org reaction link: R-HSA-425861
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Reaction input - small molecules:
1,2-diacyl-sn-glycerol
Reaction output - small molecules:
Reactome.org link: R-HSA-425861