Reaction: sphinganine 1-phosphate + H2O => sphinganine + orthophosphate
- in pathway: Sphingolipid metabolism
SGPP1 and 2 (sphingosine-1-phosphate phosphatase 1 and 2) enzymes associated with the endoplasmic reticulum membrane catalyze the hydrolysis of cytosolic sphinganine 1-phosphate to form sphinganine (dihydrosphingosine) and orthophosphate (Johnson et al. 2003; Ogawa et al. 2003).
Reaction - small molecule participants:
Pi [cytosol]
SPA [cytosol]
H2O [cytosol]
SPAP [cytosol]
Reactome.org reaction link: R-HSA-428664
======
Reaction input - small molecules:
water
sphinganine 1-phosphate
Reaction output - small molecules:
hydrogenphosphate
sphinganine
Reactome.org link: R-HSA-428664