Reaction: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6
- in pathway: Inositol transporters
The human SLC5A11 gene encodes a high affinity myo-inositol transporter (SMIT2, SGLT6) (Ostlund RE et al, 1996; Roll P et al, 2002). It can transport myo-inositol and D-chiro-inositol, together with two Na+ ions. It was thought SGLT6 could transport glucose but there is no evidence for this so far (Lin X et al, 2009).
Reaction - small molecule participants:
Na+ [cytosol]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-429571
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Reaction input - small molecules:
sodium(1+)
Reaction output - small molecules:
sodium(1+)
Reactome.org link: R-HSA-429571