Reaction: p-S256-Aquaporin-2 passively transports water into cell
Aquaporin-2 (AQP2) passively transports water across membranes according to the osmotic gradient. AQP2 is mainly expressed in principal cells of the collecting duct and connecting tubule in the kidney. AQP2 function is acutely regulated by the antidiuretc hormone vasopressin. In the presence of vasopressin AQP is phosphorylated at Ser256, As inferred from rat and mouse Ser261, Ser264, and Thr269 may also be phosphorylated. These phosphorylations are thought to influence AQP2 trafficking and compartmentalization.
Reaction - small molecule participants:
H2O [cytosol]
H2O [extracellular region]
Reactome.org reaction link: R-HSA-432065
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Reaction input - small molecules:
water
Reaction output - small molecules:
water
Reactome.org link: R-HSA-432065