Reaction: NaS2 co-transports sulphate and two sodium ions
The human gene SLC13A4 encodes a sodium/sulphate co-transporter NaS2 (Girard JP et al, 1999). NaS2 is highly expressed in placenta and testis, mainly in high endothelial venules. Kinetic experiments suggest two sodium ions co-transported for every sulphate ion (Markovich D et al, 2005).
Reaction - small molecule participants:
Na+ [cytosol]
SO4(2-) [cytosol]
SO4(2-) [extracellular region]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-433099
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Reaction input - small molecules:
sulfate
sodium(1+)
Reaction output - small molecules:
sodium(1+)
sulfate
Reactome.org link: R-HSA-433099