Reaction: NACT co-transports trivalent citrate and a sodium ion
The human SLC13A5 gene encodes a sodium-coupled citrate transporter, NACT. This gene is expressed mainly in the liver, with lower levels in brain and testis. NACT has a preference for trivalent citrate (Inoue K et al, 2002).
Reaction - small molecule participants:
CIT [cytosol]
Na+ [cytosol]
CIT [extracellular region]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-433104
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Reaction input - small molecules:
citric acid
sodium(1+)
Reaction output - small molecules:
citric acid
sodium(1+)
Reactome.org link: R-HSA-433104