Reaction: Dissociation of CaM and CAMK2 autophosphorylation
- in pathway: Ca2+ pathway
Dissociation of Ca2+/CaM from activated CAMK2 allows subsequent phosphorylations at Thr 305 and Thr 306. These phosphorylations, which occur within the CaM binding site, prevent reassociation of Ca2+/CaM (reviewed in Stratton et al, 2013).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-4332358
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-4332358