Reaction: CRAC translocates calcium from the extracellular region to the cytosol
Activation of Calcium-release-activated (CRAC) channels allows influx of calcium. The Orai component of CRAC is responsible for the selectivity of the channel, while the Stim component is responsible for activation.
Reaction - small molecule participants:
Ca2+ [cytosol]
Ca2+ [extracellular region]
Ca2+ [cytosol]
Ca2+ [extracellular region]
Ca2+ [cytosol]
Ca2+ [extracellular region]
Reactome.org reaction link: R-HSA-434798
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Reaction input - small molecules:
calcium(2+)
calcium(2+)
calcium(2+)
Reaction output - small molecules:
calcium(2+)
calcium(2+)
calcium(2+)
Reactome.org link: R-HSA-434798