Reaction: ZnT8 transports zinc into the Golgi apparatus
- in pathway: Zinc efflux and compartmentalization by the SLC30 family
Dimeric ZnT8/SLC30A8 mediates the transport of cytosolic Zn2+ into the lumen of the Golgi apparatus. The protein is expressed in human pancreatic beta cells and localizes with the Golgi apparatus and insulin-containing secretory granules (Bosco et al. 2010; Chimienti et al. 2006; Kambe et al. 2021).
Reaction - small molecule participants:
Zn2+ [Golgi lumen]
Zn2+ [cytosol]
Zn2+ [Golgi lumen]
Zn2+ [cytosol]
Reactome.org reaction link: R-HSA-437139
======
Reaction input - small molecules:
zinc(2+)
zinc(2+)
Reaction output - small molecules:
zinc(2+)
zinc(2+)
Reactome.org link: R-HSA-437139