Reaction: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)

- in pathway: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
CREB1 is phosphorylated at serine residue S119 by any of the three isoforms of ribosomal S6 kinase (RSK): RPS6KA1 (RSK1) (Song et al. 2003), RPS6KA2 (RSK3) (Schinelli et al. 2001), RPS6KA3 (RSK2) (De Cesare et al. 1998, Harum et al. 2001), and probably by RPS6KA6 (RSK4).
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-442724

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Reaction input - small molecules:
ATP(4-)
ChEBI:30616
Reaction output - small molecules:
ADP(3-)
ChEBI:456216
Reactome.org link: R-HSA-442724