Reaction: TXA2 is hydrolysed to TXB2
- in pathway: Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Thromboxane A2 (TXA2) contains an unstable ether linkage that is rapidly hydrolysed under aqueous conditions to form the biologically inert thromboxane B2 (TXB2) (Wang et al. 2001, Hamberg et al. 1975), which is excreted.
Reaction - small molecule participants:
TXB2 [endoplasmic reticulum lumen]
TXA2 [endoplasmic reticulum lumen]
H2O [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-443894
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Reaction input - small molecules:
thromboxane A2
water
Reaction output - small molecules:
thromboxane B2
Reactome.org link: R-HSA-443894