Reaction: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively
Carrier-mediated urea transport allows rapid urea movement across the cell membrane, which is particularly important in the process of urinary concentration and for rapid urea equilibrium in non-renal tissues. Two carriers exist in humans, HUT2 which is renal-specific (Olives B et al, 1996) and HUT11, which is erythrocyte-specific (Olives B et al, 1994).
Reaction - small molecule participants:
Urea [cytosol]
Urea [extracellular region]
Reactome.org reaction link: R-HSA-444126
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Reaction input - small molecules:
urea
Reaction output - small molecules:
urea
Reactome.org link: R-HSA-444126