Reaction: Zinc is an agonist of GPR39
- in pathway: Class A/1 (Rhodopsin-like receptors)
Zn2+ is a potent and effective agonist of GPR39, signaling effectively through the Gq pathway (Holst et al. 2004, 2007) and Gs (Zhang et al. 2005, Holst et al. 2007).
Reaction - small molecule participants:
Zn2+ [extracellular region]
Reactome.org reaction link: R-HSA-444572
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Reaction input - small molecules:
zinc(2+)
Reaction output - small molecules:
Reactome.org link: R-HSA-444572