Reaction: Dephosphorylation of pL1 (Y1176)
- in pathway: Recycling pathway of L1
L1 translocated to the non raft membranes of the C-domain is dephosphorylated. A number of potential candidate phosphatases exist including phosphotyrosine phosphatases. Dephosphorylation of Y1176 allows L1 binding to AP-2, an adaptor required for clathrin mediated internalization of L1.
Reaction - small molecule participants:
Pi [cytosol]
Reactome.org reaction link: R-HSA-445089
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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-445089