Reaction: ATP Hydrolysis By Myosin
- in pathway: Smooth Muscle Contraction
Once ATP is bound, myosin, which is an ATPase, uses the energy from the cleavage of the terminal phosphate to pivot the myosin head back, away from the actin filamentous chain. This change in conformation "resets" the myosin molecule, leaving it ready to bind the actin filament once more and slide the myosin filament along the actin filament, continuing the contractile cycle.
Reaction - small molecule participants:
Pi [cytosol]
Reactome.org reaction link: R-HSA-445699
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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-445699