Reaction: Calcium Binds Caldesmon
- in pathway: Smooth Muscle Contraction
Caldesmon functions in an analogous fashion to troponin in striated muscle. Once calcium has entered the smooth muscle cell, calcium levels slowly rise. Caldesmon binds calcium, freeing tropomyosin, allowing the tropomyosin to move exposing the active sites on actin for myosin binding.
Reaction - small molecule participants:
Ca2+ [cytosol]
Reactome.org reaction link: R-HSA-445704
======
Reaction input - small molecules:
calcium(2+)
Reaction output - small molecules:
Reactome.org link: R-HSA-445704